A present and global threat called Extended-Spectrum Beta-lactamases (ESBLs)

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[Extended-spectrum beta-lactamases (ESBLs) producing bacteria].

TEM- or SHV-type extended-spectrum beta-lactamases(ESBLs) are of clinical concern in Europe and the United States, whereas bacterial strains producing such types of ESBLs had not been reported in Japan for many years. Toho-1, a different type class A ESBL, has been reported in 1995, in which any prototypical enzyme has not been identified so far. At present Toho-1 is the major ESBL in Japan, ho...

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Extended - spectrum Beta - lactamases

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

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Extended-spectrum beta-lactamases.

At least 30 extended-spectrum beta-lactamases (ESB) have emerged responsible for resistance to indigestible beta-lactams (C3G) since their discovery in West Germany in 1983. Most of them are produced by enterobacteria and essentially K. pneumoniae which appeared susceptible to oxyimino-beta-lactams. A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, bloo...

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Prevalence and molecular characterization of Extended Spectrum Beta-Lactamases (ESBLs) producing Escherichia Coli and Klebsiella Pneumoniae.

UNLABELLED The aim of this study was to determine the prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae as well as genes encoding ESBLs. MATERIAL AND METHODS A total of 1207 non-repeat isolates of E. coli and K. pneumoniae were obtained from urine, tracheal aspirate, wound swab and blood from patients hospitalized at the University Clinics in Skopje. ESBL set and E-test ...

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Antibiotic Resistance Pattern and the Prevalence of Extended Spectrum Beta-Lactamases (ESBLs) in Urinary Isolates of Klebsiella Pneumoniae

Abstract Background and Objective: Klebsiella pneumoniae is an opportunistic nosocomial pathogen causing a variety of infections including urinary tract infections, pneumonia, septicemia, wound infections and infections in the intensive care units. Since the ESBL producing Klebsiella pneumoniae strains are increasingly causing urinary tract infections, we aim to assess antibiotic resistance pat...

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ژورنال

عنوان ژورنال: Current Trends On Biotechnology & Microbiology: Open Access Publishers

سال: 2018

ISSN: 2641-6875

DOI: 10.32474/ctbm.2018.01.000103